The following information was submitted:
Transactions: WSEAS TRANSACTIONS ON BIOLOGY AND BIOMEDICINE
Transactions ID Number: 29-924
Full Name: Nigel Aylward
Position: Researcher
Age: ON
Sex: Male
Address: 7 Greenhill Grove, Daisy Hill, Queensland4128
Country: AUSTRALIA
Tel: 61732081336
Tel prefix:
Fax:
E-mail address: n.aylward@qut.edu.au
Other E-mails: samkin_aylward@yahoo.com.au
Title of the Paper: A prebiotic surface catalysed synthesis of alkyl imine precursors to the aminoacids, alanine, serine and threonine
Authors as they appear in the Paper: Nigel Aylward
Email addresses of all the authors: n.aylward@qut.edu.au
Number of paper pages: 11
Abstract: Alkynes such as ethyne and propyne form weak charge-transfer, į2 -alkynyl complexes with surface catalysts such as Mg.porphin in which the alkynyl group is positively charged and the porphin has a negative charge. The enthalpy changes are -0.018 and -0.002 h, respectively. Addition of ammonia to the complexes allows the formation of Mg.2-amino ethenyl.porphin and Mg.2-amino propenyl.porphin with small enthalpy changes. and subsequent cyclic formation to Mg.1H aziridin-2yl.porphin and Mg. 2-methyl 1H aziridin-3yl.porphin complexes. The former may undergo a prototropic ring opening to form the imino precursor to the amino-acid alanine. Both complexes undergo ring opening with hydroxide anion to give the imine precursors to the amino-acids, serine and threonine. where the activation energies and enthalpy changes are,respectively, 0.072 h and -0.159h, and 0.072 h and -0.167 h. This mechanism constitutes another method for the formation of reactive, and!
unstable, imines that could facilitate the formation of aziridine-2ones, which have been predicated as important in amino acid synthesis. The reactions have been shown to be feasible from the overall enthalpy changes in the ZKE approximation at the HF and MP2 /6-31G* level.
Keywords: Alkynes, 2-amino ethenyl, 2-amino propenyl, 1h aziridin-2yl and 1h 2-methyl aziridin-3yl complexes of mg.porphin
EXTENSION of the file: .doc
Special (Invited) Session: A prebiotic surface catalysed synthesis of imines
Organizer of the Session: 618307
How Did you learn about congress:
IP ADDRESS: 203.206.160.250
