The following information was submitted:
Transactions: WSEAS TRANSACTIONS ON CIRCUITS AND SYSTEMS
Transactions ID Number: 29-160
Full Name: Miha Mo¹kon
Position: Assistant
Age: ON
Sex: Male
Address: Tr¾aska cesta 25, 1000 Ljubljana
Country: SLOVENIA
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E-mail address: miha.moskon@fri.uni-lj.si
Other E-mails: miha.moskon@gmail.com
Title of the Paper: Toward in vivo digital synchronous sequential circuits
Authors as they appear in the Paper: Miha Mo¹kon, Monika Cigliè, Nikolaj Zimic, Miha Mraz
Email addresses of all the authors: miha.moskon@fri.uni-lj.si, monika.ciglic@ki.si, niko.zimic@fri.uni-lj.si, miha.mraz@fri.uni-lj.si
Number of paper pages: 10
Abstract: We present the model of a first digital synchronous sequential circuit, i.e. 1-bit synchronous counter, which is about to be realized within the living cell. Mathematical model was constructed upon gene expression based logic with ordinary differential equations (ODEs), particularly Hill equations. The behaviour of the counter was simulated in Matlab/Simulink environment. With the promising simulation results presented in the paper physical realization of the circuit described within the living cell can be initiated. Introduction of synchronization with a special signal, i.e. clock signal, brings many benefits to the field. Realization of such circuit would therefore present an important step toward the construction of complex biological information processing capable systems.
Keywords: Synthetic biology, Protein-based computing, Sequential logic, Synchronization, Ordinary differential equations, Biological modelling, Circuits, Master-Slave flip-flop
EXTENSION of the file: .pdf
Special (Invited) Session: Towards the realization of synchronous sequential biological circuits
Organizer of the Session: 699-177
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