The following information was submitted:
Transactions: WSEAS TRANSACTIONS ON ENVIRONMENT AND DEVELOPMENT
Transactions ID Number: 53-679
Full Name: Benbouzid Houneida
Position: Assistant Professor
Age: ON
Sex: Female
Address: 10, rue wright; Beau séjour.
Country: ALGERIA
Tel: 00 213 661 37 69 75
Tel prefix: 00 213
Fax: 00 213 38 86 85 10
E-mail address: benbouzid_h@yahoo.fr
Other E-mails: Mohamed.Benbouzid@univ-brest.fr, fatima_benbouzid@yahoo.fr, malika.berredjem@univ-annaba.org
Title of the Paper: Toxic effect of novel phosphoramidate on Paramecium aurelia: Growth kinetics and special emphasis on respiratory metabolism
Authors as they appear in the Paper: Benbouzid Houneida, Berrebah Houria, Berredjem Malika and DJEBAR
Email addresses of all the authors: benbouzid_h@yahoo.fr,malika.berredjem@univ-annaba.org, r_djebar@yahoo.fr
Number of paper pages: 10
Abstract: ABSTRACT: -The continuous increase in the number of new chemicals as well as the discharges of solid and liquid wastes triggered the need for simple and inexpensive bioassays for routine testing. In recent years, there has been increasing development of methods (particularly rapid tests) for testing environmental samples. This paper describes the quick toxic evaluation of a novel synthetic compound: phosphoramidate derivative B at different concentrations (2, 4 and 8 µM) for 72 h on Paramecium aurelia. We recorded that B concentrations affect the growth of Paramecium in concentration-dependent manner; also it decreases the growth rate and increases response percentage in concentration-dependent manner. The value of LC50 obtained for these protozoa was estimated at 4.9693 µM after 24 hours of exposure. The respiratory metabolism of protozoan is perturbed at three concentrations, noting that the oxygen consumption was significantly increased at high concentrations af!
ter 18 hours of exposure. The results indicate that the Paramecium toxicity assay could be used as a complimentary system to rapidly elucidate the cytotoxic potential of insecticides. The major advantages associated with these tests are: they are inexpensive, simple, user-friendly, space saving, and seem to be attractive alternatives to conventional bioassays.
Keywords: Phosphoramidate B, Paramecium aurelia, Cytotoxic, Tests Growth kinetics, Respiratory metabolism
EXTENSION of the file: .doc
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