The following information was submitted:
Transactions: WSEAS TRANSACTIONS ON COMPUTERS
Transactions ID Number: 32-854
Full Name: Dana Alexandrescu
Position: Lecturer
Age: ON
Sex: Female
Address: Avram Iancu, No 11 Brasov
Country: ROMANIA
Tel: +40721375463
Tel prefix:
Fax: +40368427697
E-mail address: adanaso1970@yahoo.com
Other E-mails: rdbogdan@gmail.com
Title of the Paper: Staging of macronodular versus nodular non small cell lung carcinoma and the role of PET-CTi
Authors as they appear in the Paper: Dana Alexandrescu, Milena Man, Bogdan Ratiu-Duma, Liliana Rogozea
Email addresses of all the authors: adanaso1970@yahoo.com, manmilenaadina@yahoo.com, rdbogdan@gmail.com, r_liliana@yahoo.com
Number of paper pages: 11
Abstract: 18fluorodeoxyglucose positron emission tomography (PET) imaging provides information on the biochemical processes that may precede gross anatomic change. PET imaging is potentially useful in tumor imaging in particular due to the uptake of the radiolabeled glucose analog 18fluorodeoxyglucose (18FDG) by tumor tissue as a result of increased glycolysis in some cancers as compared with most normal tissue. [18F]2-Fluoro-2-deoxy-glucose positron emission tomography is an important functional imaging technique for the diagnosis, staging and follow-up of patients with macronodular versus nodular nonsmall cell lung carcinoma. Thus, the authors tried to assess the role of PET-CTi to the staging of the non small cell lung cancer and to demonstrate the diagnose superiority, improveness and accuracy among other image methods such as CT, PET, PET-CTv by analyzing through comparison 2 groups of patients, first with nodules smaller than 3 cm and the second one with nodules larger!
than 3 cm. In a prospective study, integrated PETâ€"CT was performed in 50 patients with proven orsuspected nonâ€"small-cell lung cancer. CT and PET alone, visually correlated PET and CT, and integrated PETâ€"CT were evaluated separately, and a tumorâ€"nodeâ€"metastasis (TNM) stage was assigned on the basis of image analysis. The standard of reference was histopathological assessment of tumor stage and node stage. Extrathoracic metastases were confirmed histopathologically or by at least one other imaging method. A paired sign test was used to compare integrated PETâ€"CT with the other imaging methods. Integrated PETâ€" CT had better diagnostic accuracy than the other imaging methods. Tumor staging was significantly more accurate with integrated PETâ€"CT than with CT alone (P=0.001), PET alone (P<0.001), or visual correlation of PET and CT (P=0.013); node staging was also significantly more accurate with integrated PETâ€"CT than with PET alone (P=0.013).Integrated PETâ€"CT!
improves the diagnostic accuracy of the staging of nonâ€"small-cell l
ung cancer.
Keywords: Diagnostic accuracy, PET-CTi, Tumor staging, Macronodular nonsmall lung carcinoma, Nodular nonsmall lung carcinoma.
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