The following information was submitted:
Transactions: WSEAS TRANSACTIONS ON BIOLOGY AND BIOMEDICINE
Transactions ID Number: 52-113
Full Name: Milena Adina Man
Position: Senior Lecturer
Age: ON
Sex: Female
Address: Cluj Napoca, Caraiman 3 Street
Country: ROMANIA
Tel: 0040722459586
Tel prefix:
Fax:
E-mail address: manmilenaadina@yahoo.com
Other E-mails:
Title of the Paper: Increased mortality risk in patients with tuberculosis
Authors as they appear in the Paper: Man Milena Adina, Antigona Trofor, Dana Alexandrescu , Elena Dantes, Pop Monica, Ruxandra Rajnoveanu, Cosmina Bondor, Cosmina Magdau
Email addresses of all the authors: manmilenaadina@yahoo.com, atrofor@yahoo.com, adanaso71@yahoo.com, elenadantes@yahoo.com
Number of paper pages: 10
Abstract: The tuberculosis mortality rate has been declining steadily for many years. Despite the availability of chemotherapy, mortality remains high among patients hospitalized for tuberculosis. We performed a study to define the factors associated with mortality following in hospital diagnosis of tuberculosis between January 1998- December 2004 on 100 patients who died in Cluj Napoca Pneumology Hospital and compared the results with a second group with 120 TB patients with favourable evolution. We tried to identify what risk factors are associated with high mortality among tuberculosis patients under treatment. . Also, we evaluated the main causes of death. Gender is not prognostic factor for Tb attributable deaths (OR=1.11 CI 95% 0.52-2.41 p=0.77) Patients over 50 years had a high risk of death (p=0,001). Urban residence was a significant prognostic factor p=0.002 (OR=2.65 CI 95% 1.37-5.17) and retired subjects had a relative risk of death. (Retired: p=0, 01 OR = 1.99!
). TB history family was a significant prognostic element (OR=4.55, p=0.0004), previous history of TB was associated with death. (OR=56.03 and p=0.0000000000001), homeless and insalubrious home were statistically significant prognostic factor. (P=0.00000002), alcohol abuse are factor with an unfavourable influence. Associated co morbidity were not revealed as death factors, but impaired general condition is a risk factor for death (OR= 4, 52). Patients with cavitations have risk of death OR=21, 28, near patients with positive smear (M+) and positive culture (OR=4, 57). Treatment failure as relapse and chronic TB were associated with increase of mortality (OR=56, 03) The identification of potentially reversible factors such as malnutrition, non adherence to treatment, respiratory failure suggests specific interventions that may lead to improvement in patients outcomes, can improve the management of TB cases and avoid increased mortality in such patients.
Keywords: tuberculosis, mortality risk, TB mortality, relative risk, TB control, prognosis factors
EXTENSION of the file: .pdf
Special (Invited) Session:
Organizer of the Session:
How Did you learn about congress:
IP ADDRESS: 94.53.197.6
