Thursday, 25 September 2008

Wseas Transactions

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Transactions: WSEAS TRANSACTIONS ON BIOLOGY AND BIOMEDICINE
Transactions ID Number: 28-222
Full Name: Alexandra Oliveros
Position: Researcher
Age: ON
Sex: Female
Address: 4208 Monticello Gardens Pl, Apt 301 Tampa, FL 33613
Country: UNITED STATES
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E-mail address: alexandra_oliveros@ieee.org
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Title of the Paper: "Performing DNA Microarray Image Processing Through the Implemention of an Automatic Spot Addressing Method and a Contour Based Segmentation Approach"
Authors as they appear in the Paper: Alexandra Oliveros, Miguel Sotaquira
Email addresses of all the authors: alexandra_oliveros@ieee.org, msotaquira@uninorte.edu.co
Number of paper pages: 10
Abstract: Disease diagnosis and treatment through gene expression analysis have become a widely used technique for genetecists around the world. Gene expression analysis can be done using DNA microarrays, which are based on the hybridization of a tissue's DNA sequence into a substrate and the further processing of the image conformed by the genes as green, red or yellow spots. The DNA microarray image processing involves, finding the location of the spots and the quantification of their expression level. This paper dicusses the steps needed to perform DNA microarray image analysis, such as: the spot addressing, spot segmentation and gene information extraction. Likewise, a tool that performs DNA microarray image analysis through the locations of the spots, based on the image projections and the identification of the spot signal using contour based segmentation, is described.
Keywords: Contour segmentation, DNA microarrays, edge detection, image processing, segmentation, spot addressing
EXTENSION of the file: .pdf
Special (Invited) Session: Implementing Automatic Spot Addressing and Contour Based Segmentation in Microarray Image Analysis
Organizer of the Session: 595-543
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