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Transactions: WSEAS TRANSACTIONS ON BIOLOGY AND BIOMEDICINE
Transactions ID Number: 31-420
Full Name: Yao-Ming Yu
Position: Ph.D. Candidate
Age: ON
Sex: Female
Address: 1, Sec. 3, Chung-hsiao E. Rd., Taipei, 10608, Taiwan, R.O.C.
Country: TAIWAN
Tel: 886-2-2771-2171x2249
Tel prefix: Mr.
Fax: 886-2-2731-7120
E-mail address: wtjacky@ms68.hinet.net
Other E-mails: eduymyu@tp.edu.tw,liang@saihs.edu.tw,ymyu@saihs.edu.tw
Title of the Paper: Implementation of extracellular neural recording system and study of evoked signal preprocessing method
Authors as they appear in the Paper: Yao-Ming Yu, Wen-Liang Tsai, Rong-Chin Lo
Email addresses of all the authors: eduymyu@tp.edu.tw,liang@saihs.edu.tw,ymyu@saihs.edu.tw
Number of paper pages: 10
Abstract: A multichannel recording system of extracellular cortex is utilized to acquire the neural signal of primary somatosensory cortex in rats. The extracellular neural recording system includes mainly the acquisition sub-system, the monitoring sub-system and the analyzing sub-system. We use the microwire array electrode to record different signal of three types; those are from on air, from S1HL without stimulation and from S1HL with stimulation by scratching the claw of the left hind leg using a brush. A signal processing system is applied to deal with the saved data. Through the method of spectral subtraction, we can reduce the influence of noise. Beside, nonlinear energy operator algorithm is employed to detect the timestamp of evoked potential by external stimuli. The signals are according to the time interval between preceding and following of timestamp to separate apart into every section. Each section can proceed to extract the features from every small segment of!
the signals and classify evoked potential segments that own similar features to the same group in the future. Finally, the information of the monitor system are apply to verify the accuracy of spike detection that the information comprises the action of external stimulus, the waveform of neural signal and the voice of speaker, simultaneously. Through the result of experiments, the developed recording system is suitable for intracortical signals recording; the proposed method is feasible and effective for noise reduction and spike detection of extracellular evoked potentials.
Keywords: Microwire array electrode, Extracellular recording, Somatosensory evoked potential, Brain machine interface, Moving average, Spectral subtraction, Nonlinear energy operator
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