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Transactions: WSEAS TRANSACTIONS ON BIOLOGY AND BIOMEDICINE
Transactions ID Number: 31-744
Full Name: surekha kamath
Position: Ph.D. Candidate
Age: ON
Sex: Female
Address: ice mit manipal
Country: INDIA
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E-mail address: surekakamath2k4@yahoo.com
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Title of the Paper: Simulation study on Control of Glucose in Type I diabetic Patients
Authors as they appear in the Paper: Surekha Kamath*, V.I.George*, Sudha Vidyasagar**
Email addresses of all the authors: surekakamath2k4@yahoo.com,
Number of paper pages: 10
Abstract: : Maintaining the glucose concentration in normoglycemic range in Type I diabetic patients is challenging. In this study H‡ control is applied for the insulin delivery to prevent the hyperglycemic levels in a type I diabetic patient. From a control theory point of view, the blood glucose regulation problem is reformulated as a tracking one. A glucose tolerance curve (GTC) validated from several healthy subjects is used as reference signal. A nonlinear compartmental model is linearized around nominal condition. And reduced for controller synthesis. H‡ design is carried out using Riccati equation based. The performance of the controllers was studied by implementing them into the nonlinear model. Sensitivity and Complementary sensitivity functions show the nominal and robust performance of the closed loop system
Keywords: Glucose insulin modeling, mathematical modeling, H‡ control, Robust control.
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