The following information was submitted:
Transactions: WSEAS TRANSACTIONS ON BIOLOGY AND BIOMEDICINE
Transactions ID Number: 42-618
Full Name: Jelenka Savkovic-Stevanovic
Position: Professor
Age: ON
Sex: Female
Address: Faculty of Technology and Metallurgy, Belgrade University, Belgrade Serbia
Country: YUGOSLAVIA
Tel: 381113303771
Tel prefix: 001
Fax: 381113370387
E-mail address: savkovic@tmf.bg.ac.rs
Other E-mails: stevanoviccacr@gmail.com
Title of the Paper: Regulatory mechanism of transcriptional activity
Authors as they appear in the Paper: Jelenka Savkovic-Stevanovic
Email addresses of all the authors: savkovic@tmf.bg.ac.rs
Number of paper pages: 11
Abstract: Abstract:-Mammalian liver is a major site of purine nucleotide synthesis and provides purines in the form of bases or nucleosides to be salvaged and utilized by those tissues incapable of synthetizing purines de novo. The biomedical important is de novo synthesis which is permiting purine and pyrimidine analogs with potential as anticancer drugs to be incorporated into DNA. The synthesis rates of purine and pyrimidine oxyribonucleotides and deoxyribonucleotides are subject to precise regulation. The most important regulator of de novo purine biosynthesis is the intracellular concentration of phosphoribosy l-pyrophosphate-phosphoribosyl amine. In this paper sensitivity to product inhibition by reacting nucleotides was studied. The hybridization reaction is examined as probability reactions between oligonucleotides.
Keywords: Key-Words - Biosynthesis, enzyme, catabolism, nucleosides, nucleotides, amidotransferase, cross-regulation, hybridization, stacking interaction.
EXTENSION of the file: .rtf
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