The following information was submitted:
Transactions: INTERNATIONAL JOURNAL of BIOLOGY and BIOMEDICAL ENGINEERING
Transactions ID Number: 19-516
Full Name: Cornelia Aida Bulucea
Position: Associate Professor
Age: ON
Sex: Female
Address: University of Craiova, Faculty of Electromechanical and Environmental Engineering, Bd. Decebal 107, Craiova
Country: ROMANIA
Tel: 435255
Tel prefix: +40251
Fax: +40251435255
E-mail address: abulucea@gmail.com
Other E-mails: aidan5678@gmail.com
Title of the Paper: The infectious etiology of second trimester spontaneous abortion reflected in the peripheral blood
Authors as they appear in the Paper: Carmen A. Bulucea, Nikos E. Mastorakis, Mariana F. Paun, and Alina D. Neatu
Email addresses of all the authors: abulucea@gmail.com , mastorakis4567@gmail.com, aneatu@gmail.com
Number of paper pages: 12
Abstract: The infection¡¯s role in causing or facilitating preterm labor and abortion in the second trimester is nowadays increasingly described. The goal of this study was to quantitatively measure the serum CRP by immunoturbidimetric technique to establish the serum CRP concentration in the second trimester of uncomplicated pregnancy and the sensibility of this parameter in complicated advanced pregnancies. This prospective and controlled study was conducted on 75 pregnant, non smoking women with a gestational age between 13 and 27 weeks, checked in the sections of the Obstetrics and Gynecology Clinic of the University of Medicine and Pharmacy Craiova, whose serum CRP was dosed in parallel with leukocytes counting. The patients were split in several study groups including a control group. The data analysis indicates the lack of a positive correlation between serum CRP concentration and gestational age in the second trimester of normal pregnancy after 20 weeks. The results !
indicate a significant increase of the serum CRP concentration (but not leukocytes number) at 24 hours postabortum followed by a progressive decrease of at least 18% at 48 hours after second trimester uncomplicated abortion. Only the pregnancy complicated by urogenital bacterial infections is accompanied by pathological values of serum CRP significantly elevated with respect to those in a normal pregnancy or one complicated with threatened abortion of unknown cause and non-evolutive, or prior recurrent abortions. 72% of pregnancies complicated with urogenital bacterial infections are accompanied by pathological values of serum CRP (but not of the leukogram), while 100% of pregnant women with serum CRP concentrations ¡Ý 2 mg/dl were diagnosed with chorioamnionitis or acute pyelonephritis. The obtained results suggest that a repeated measurement of the serum CRP concentration could be a valuable predictive marker for intrauterine infection.
Keywords: CRP, intrauterine infection, second trimester pregnancy.
EXTENSION of the file: .pdf
Special (Invited) Session: Evaluating the Infection in the Second Trimester of Pregnancy by C-Reactive Protein Dosing
Organizer of the Session: 103-113
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