The following information was submitted:
Transactions: INTERNATIONAL JOURNAL of BIOLOGY and BIOMEDICAL ENGINEERING
Transactions ID Number: 19-517
Full Name: Cornelia Aida Bulucea
Position: Associate Professor
Age: ON
Sex: Female
Address: University of Medicine and Pharmacy of Craiova, Str.Petru Rares, no.2-4, 200349
Country: ROMANIA
Tel: 435255
Tel prefix: +40251
Fax: +40251435255
E-mail address: abulucea@gmail.com
Other E-mails: aidan5678@gmail.com
Title of the Paper: Therapeutic abortion in the second trimester of pregnancy
Authors as they appear in the Paper: Carmen A. Bulucea, Nikos E. Mastorakis, Mariana F. Paun, and Alina D. Neatu
Email addresses of all the authors: abulucea@gmail.com , mastorakis4567@gmail.com, aneatu@gmail.com
Number of paper pages: 12
Abstract: Late therapeutic abortion represents termination of pregnancy in the second trimester, before the moment of reaching fetal viability, with the purpose of protecting the mother's health. The techniques for terminating a pregnancy in the second trimester can be classified as surgical ones (cervical dilation followed by uterine evacuation and laparotomy with hysterotomy or hysterectomy) and medical ones (intravenous oxytocin solution, intraamniotic hyperosmotic solution, prostaglandins and intraamniotic, extra-ovular, parenteral, oral and vaginal analogues of prostaglandins, just as sensitizers of the myometrium before applying prostaglandins and various combinations of the above mentioned). Prostaglandins are preferentially used nowadays to terminate second trimester pregnancy because of the drawbacks presented by the other surgical and medical methods (used in this purpose), such as limited efficiency and/or their severe complications. This study is intended to exte!
nd the existent experience regarding the intravaginal misoprostol for second trimester therapeutic abortion induction. This prospective clinic study selected 20 pregnant women, with a gestational age of 15 to 27 weeks who have been checked in the Clinic of Obstetrics-Gynecology of the University of Medicine and Pharmacy of Craiova, for therapeutic abortion induction. The 20 pregnant women received in PVF a 200µg misoprostol tablet each 12 hours, respecting strictly the protocol developed by the authors. Our results demonstrate clearly that in the conditions of therapeutic correction/counteraction of the complications associated to pregnancies that must be terminated in the second trimester, the rate of abortion in the first 24 hours from the intravaginal misoprostol application (following the protocol developed by the authors) can become 100%, while the average duration of the abortion induced in the same manner drops to under 12 hours. Our observations indicate a rate of c!
omplete abortion of 60%, which reduced significantly the rate of posta
bortum curettage, in the same time opening new perspectives to fetal transplantation and noninvasive investigation of the amniotic fluid.
Keywords: induced abortion, intravaginal misoprostol, second trimester abortion.
EXTENSION of the file: .pdf
Special (Invited) Session: Medically Induced Abortion in Second Trimester with Intravaginal Misoprostol
Organizer of the Session: 103-129
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