Wednesday 24 March 2010

Wseas Transactions

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Transactions: WSEAS TRANSACTIONS ON CIRCUITS AND SYSTEMS
Transactions ID Number: 89-584
Full Name: Nina Korlina Madzhi
Position: Senior Lecturer
Age: ON
Sex: Female
Address: Faculty of Electrical Engineering, Universiti Teknologi MARA,40450 Shah Alam,Selangor
Country: MALAYSIA
Tel: 55436072
Tel prefix: +603
Fax: +603-55435077
E-mail address: nina6875@yahoo.com
Other E-mails: ninak654@salam.uitm.edu.my
Title of the Paper: Piezoresistive Microcantilever Biosensor Potentiometric Signal Transduction for Human Stress Measurement
Authors as they appear in the Paper: Nina Korlina Madzhi, Anuar bin Ahmad, Lee Yoot Khuan, Mohd Firdaus Abdullah
Email addresses of all the authors: nina6875@yahoo.com
Number of paper pages: 10
Abstract: This paper deals with the development of Piezoresistive Microcantilever biosensor and the signal transduction to detect human stress by using salivary alpha amylase activity. A Piezoresistive Microcantilever biosensor can be used to detect saliva-amylase activity by deflecting upon interaction with a specific receptor. By measuring the amount of bending the microcantilever beam experiences in response to interactions with the molecules, and the amount of analyte in the solution can be quantified. When the Microcantilever beam deflects it caused the stress change within the microcantilever beam and applied strain to the piezoresistor material thereby causing the resistance change which can be measured with the Wheatstone Bridge circuit. The Piezoresistive Microcantilever sensor integrated with transducer components converts the biochemical signal into measurable signal when it react with salivary amylase enzyme. The enzyme concentration signal is converted to a volt!
age signal by the transducer. The device was designed specifically that it enables the small resistivity change due to the enzymatic reaction to be measured.
Keywords: Biosensor, Piezoresistive, Microcantilever, Signal Transduction, Resistance change, Saliva, Alpha Amylase
EXTENSION of the file: .doc
Special (Invited) Session: Development and Electrical Measurements of Piezoresistive Microcantilever Biosensor Signal Transduction for Human Stress Measurement
Organizer of the Session: 640-641
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