Monday, 28 June 2010

Wseas Transactions

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Transactions: WSEAS TRANSACTIONS ON BIOLOGY AND BIOMEDICINE
Transactions ID Number: 52-215
Full Name: Shi-ping Luh
Position: Professor
Age: ON
Sex: Male
Address: 10F, No. 565, Sec 2, Da Ya Rd. St Martin De Porres Hospital, Chia-Yi City 60069
Country: TAIWAN
Tel: 011-886-5-2756000 ext 1003
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E-mail address: luh572001@yahoo.com.tw
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Title of the Paper: Excision of Pulmonary Nodules or Masses in Patients with Known Malignancies through Video-Assisted Thoracoscopic (VATS) Surgery
Authors as they appear in the Paper: Shi-Ping Luh
Email addresses of all the authors: luh572001@yahoo.com.tw
Number of paper pages: 10
Abstract: Introduction. The development of computed tomography (CT) have made more pulmonary nodules being found in patients with known malignancies during work-up or follow-up. Excision through video-assisted thoracoscopic surgery (VATS) can be applied as a reliable method for the diagnosis and treatment of these nodules. Patients and Methods. From July 1996 to June 2009, 78 patients with newly diagnosed or prior treated malignancies were found with indeterminate pulmonary nodules or masses which were excised through VATS. Forty-three males and thirty-five females were included with ages ranging from 14 to 88 (median: 61) years. Their known malignancies arose from the colo-rectal (26 patients), breast (17 patients), head and neck (10 patients), lung (8 patients), soft tissue sarcoma (6 patients) and others (12 patients). Since July 2001, CT-guided localization before VATS was used in 13 patients with small (<10mm) or deep (>5mm) pulmonary nodules. All the visible tumors !
were resected in patients undergoing this procedure for treatment. However, only one to two nodules were removed in patients for confirming diagnosis. Results: The resected tumor size ranged from 0.2cm to 6.5cm (Median: 1.5 cm) and the number of the resected tumors ranged from 1 to 5. All lesions were successfully resected through VATS. There were 52 of them undergoing this procedure for diagnosis and treatment (including malignant and benign lesions) and 26 of them for diagnosis only. The indication of the use of pre-operative CT guided localization included small lesion in 2, deep seated lesion in 3, both small an deep seated lesion in 6 and dense adhesion which can be predicted by prior intrathoracic radiation or operation history in 2 patients. Among these 78 patients, metastatic malignancies were diagnosed in 43 of them, 8 of them were secondary primary pulmonary neoplasms, and 27 of them were benign lesions (20 of them were granuloma with or without evidence of tub!
erculi infection). Subsequent conversion to open procedure (a utility
incision from 4 to 11cm) was performed in 6 of the 8 patients with second primary lung carcinoma and 6 patients with the size of metastatic tumors larger than 3 cm in diameter. The median length of chest tube indwelling was 4 days. Over 90% (71/78) of patients can return to normal daily activity within 14 days. Conclusion: Resection of pulmonary nodules or masses through VATS for patients with prior or at present malignancies can be helpful in their early and reliable diagnosis as well as minimally invasive and effective treatment. Pre-operative CT-guided localization can facilitate subsequent resection and avoid possible open procedures.
Keywords: video-assisted thoracoscopic surgery, computed tomography, pulmonary nodule, malignancy, localization.
EXTENSION of the file: .pdf
Special (Invited) Session: Invited lecture of WSEAS in surgery, held in Malta.
Organizer of the Session: Alkis Polyrakis
How Did you learn about congress: luh572001@yahoo.com.tw
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