The following information was submitted:
Transactions: INTERNATIONAL JOURNAL of BIOLOGY and BIOMEDICAL ENGINEERING
Transactions ID Number: 20-616
Full Name: Hassane Oudadesse
Position: Professor
Age: ON
Sex: Male
Address: 263, av du Général Leclerc, Campus de beualieu, Rennes
Country: FRANCE
Tel: +(33 2 23 23 66 59
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E-mail address: hassane.oudadesse@univ-rennes1.fr
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Title of the Paper: 2- Physico-chemical assessment of biomimetic nano-hydroxyapatite/polymer matrix for use in bony surgery
Authors as they appear in the Paper: H. Oudadesse, A. Mostafa, X. V. Bui, E. Foad, G. Kamal, Y. Legal and G. Cathelineau
Email addresses of all the authors: hassane.oudadesse@univ-rennes1.fr, e-mail: amanieg1@yahoo.com, vuongbx@yahoo.com, yann.legal@univ-rennes1.fr, guy.cathelineau@uni-rennes1.fr
Number of paper pages: 8
Abstract: Millions of people are suffering from bone defect arising from trauma, tumor or bone diseases. Therefore, there is a growing need for the development of biocomposites with excellent bioactivity and compatibility. In this study, nano-hydroxyapatite was elaborated by using polyvinyl alcohol (PVA) and polyvinylpyrrolidone (PVP) under mild temperature condition. Comparison with pure nano-hydroxyapatite prepared by precipitation method was investigated. The main goal is to highlight the effects of the introduction of polymers on the physico-chemical properties, morphology and on the chemical reactivity and bioactivity for applications in bony surgery. TEM showed a nanosphere hydroxyapatite with an average diameter 45 nm obtained by using PVA. Nano-rods HA with an average dimensions 13 nm width and 156 nm length were obtained by using, PVP. "In-vitro" physiological stability and solubility of the investigated samples was performed by soaking powder in Simulated Body Flui!
d under physiological condition. Characterization by XRD, FT-IR SEM-EDS and ICP-OES were performed to identify phases, microstructure and then the chemical reactivity and bioactivity after soaking in SBF to evaluate the bioactivity kinetics. Crystals on the polymer fibril matrix exhibited certain orientation. Bone like apatite layer onto the surfaces is confirmed after post immersion in SBF by FT-IR, SEM-EDS and XRD. The polymer matrix controlled the dissolution precipitation reactivity with specific rate without change on the pH of the surrounding physiological body fluid.
Keywords: Bioactivity, biomimetic, "in vitro" assay, nano-Hydroxyapatite, polymer matix composite, polyvinyl alcohol, polyvinylpyrrolidone, precipitation.
EXTENSION of the file: .doc
Special (Invited) Session: Studies of Doped Biomimetic Nano-Hydroxyapatite/polymer Matrix Composites for Applications in Biomedical Field
Organizer of the Session: 650-460
How Did you learn about congress: hicham.benhayoune@univ-reims.fr
IP ADDRESS: 148.60.83.216
